COMPARATIVE-STUDIES OF ASPARAGINE-LINKED SUGAR CHAINS OF IMMUNOGLOBULIN-G FROM 11 MAMMALIAN-SPECIES

被引：27

作者：

HAMAKO, J

MATSUI, T

OZEKI, Y

MIZUOCHI, T

TITANI, K

机构：

[1] FUJITA HLTH UNIV,DIV BIOMED POLYMER SCI,TOYOAKE,AICHI 47011,JAPAN

[2] FUJITA HLTH UNIV,INST COMPREHENS MED SCI,DIV PATHOL BIOCHEM,TOYOAKE,AICHI 47011,JAPAN

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1993年 / 106卷 / 04期

关键词：

D O I：

10.1016/0305-0491(93)90056-B

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Asparagine-linked sugar chains released by hydrazinolysis from IgGs of porcine, equine, bovine, goat, ovine, canine, rabbit, guinea-pig and rat were comparatively analyzed by microsequencing and lectin affinity chromatography. 2. Sugar chains of all IgGs basically consisted of biantennary complex-type oligosaccharides containing 0-2 sialic acid residue(s). More than 70% of the oligosaccharides were neutral, except for guinea-pig IgG, and fucosylated trimannosyl core structures were dominant except for rabbit IgG. Bisecting N-acetylglucosamine residue was absent in porcine and equine IgGs. 3. A large quantity of galactose-less oligosaccharides were present in IgGs of porcine, equine, canine and rat.

引用

页码：949 / 954

页数：6

共 23 条

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