BALHIMYCIN, A NEW GLYCOPEPTIDE ANTIBIOTIC PRODUCED BY AMYCOLATOPSIS SP Y-86,21022 - TAXONOMY, PRODUCTION, ISOLATION AND BIOLOGICAL-ACTIVITY

被引：66

作者：

NADKARNI, SR

PATEL, MV

CHATTERJEE, S

VIJAYAKUMAR, EKS

DESIKAN, KR

BLUMBACH, J

GANGULI, BN

LIMBERT, M

机构：

[1] HOECHST INDIA LTD,RES CTR,DEPT MICROBIOL,MULUND W,BOMBAY 400080,INDIA

[2] HOECHST AG,SBU ANTIINFECT,D-65926 FRANKFURT,GERMANY

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 03期

关键词：

D O I：

10.7164/antibiotics.47.334

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new glycopeptide antibiotic, balhimycin, has been isolated from the fermentation broth of a Amycolatopsis sp. Y-86,21022. Balhimycin belongs to the vancomycin class of glycopeptides and contains a dehydrovancosamine sugar. The biological activity of balhimycin has been compared extensively with that of vancomycin against methicillin resistant staphylococci and also against anaerobes. Balhimycin is marginally superior to vancomycin in its in vitro activity against anaerobes and in its bactericidal properties.

引用

页码：334 / 341

页数：8

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