RAT SERUM AMYLOID-P COMPONENT - ANALYSIS OF CDNA SEQUENCE AND GENE-EXPRESSION

被引：21

作者：

DOWTON, SB

MCGREW, SD

机构：

[1] WASHINGTON UNIV,SCH MED,EDWARD MALLINCKRODT DEPT PEDIAT,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,SCH MED,JAMES S MCDONNELL DEPT GENET,ST LOUIS,MO 63110

来源：

BIOCHEMICAL JOURNAL | 1990年 / 270卷 / 02期

关键词：

D O I：

10.1042/bj2700553

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

cDNA clones for rat serum amyloid P component (SAP) were isolated, and the derived amino acid sequence for pre-SAP was determined from the complete nucleotide sequence. Rat SAP is encoded by ~1 kb of mRNA, and the mature SAP protein is predicted to be 208 amino acids long. An increase in hepatic mRNA levels of rat SAP was found after administration of lipopolysaccharide, and SAP mRNA levels in livers of unstimulated male rats were lower than in hepatic RNA from female rats.

引用

页码：553 / 556

页数：4

共 24 条

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