DISSOCIATION OF PROLACTIN RESPONSE TO THYROTROPIN-RELEASING-HORMONE AND METOCLOPRAMIDE IN CHRONIC RENAL-FAILURE

被引：14

作者：

LEROITH, D

DANOVITZ, G

TRESTAN, S

SPITZ, IM

机构：

[1] SHAARE ZEDEK GEN HOSP, DEPT ENDOCRINOL & METAB, JERUSALEM, ISRAEL

[2] BEN GURION UNIV NEGEV, FAC HLTH SCI, SOROKA MED CTR, DEPT MED, BEER SHEVA 84120, ISRAEL

[3] BEN GURION UNIV NEGEV, FAC HLTH SCI, SOROKA MED CTR, DEPT NEPHROL, BEER SHEVA 84120, ISRAEL

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1979年 / 49卷 / 06期

关键词：

D O I：

10.1210/jcem-49-6-815

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

PRL secretion was evaluated in 14 males with chronic renal failure on long term hemodialysis. Twelve had basal hyperprolactinemia. Ten subjects were challenged with TRH in doses ranging from 200-1000 μg. None of them responded to 200 or 500 μg TRH, although 2 of 4 subjects tested did respond to 1000 μg TRH. In contrast, all 4 subjects challenged with metoclopramide did have PRL responses which were indistinguishable from those of the controls. These results indicate that there is a dissociation in responsiveness to metoclopramide and TRH in chronic renal failure. © 1979 by The Endocrine Society.

引用

页码：815 / 817

页数：3

共 15 条

[1] METABOLISM AND EXCRETION OF EXOGENOUS THYROTROPIN-RELEASING HORMONE IN HUMANS [J].