INDUCED SPUTUM AND CYTOLOGICAL DIAGNOSIS OF LUNG-CANCER

被引:27
作者
KHAJOTIA, RR [1 ]
MOHN, A [1 ]
POKIESER, L [1 ]
SCHALLESCHAK, J [1 ]
VETTER, N [1 ]
机构
[1] PULMOLOG ZENTRUM, DEPT CYTOL, A-1145 VIENNA, AUSTRIA
关键词
D O I
10.1016/0140-6736(91)91839-M
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diagnosis of lung cancer by examination of induced sputum specimens for malignant cells may be a valuable alternative to diagnosis by bronchoscopy. Patients suspected of having lung cancer were recruited and randomly distributed into two groups, one group (n = 34) having sputum induced by use of an ultrasonic nebuliser before bronchoscopy, and the other (n = 33) undergoing ordinary expectoration before bronchoscopy. 25 patients in the induced-sputum group were diagnosed as having primary lung cancer, induced sputum was positive for malignant cells in 21 of these patients (84%), whereas bronchoscopy was positive in 23 (92%) (not significantly different). In comparison, ordinary sputum was positive in 15 of 29 patients (52%) diagnosed as having primary lung cancer, whereas bronchoscopy was positive in 28 (97%) (p < 0.001). Induction of sputum by an ultrasonic nebuliser was an effective procedure for diagnosis of primary lung cancer.
引用
收藏
页码:976 / 977
页数:2
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