INITIAL OBSERVATIONS ON THE DISTRIBUTION OF CANNABINOID RECEPTOR-BINDING SITES IN THE HUMAN ADULT BASAL GANGLIA USING AUTORADIOGRAPHY

被引:16
作者
MAILLEUX, P [1 ]
VERSLIJPE, M [1 ]
VANDERHAEGHEN, JJ [1 ]
机构
[1] UNIV LIBRE BRUXELLES,ERASME ACAD HOSP,B-1070 BRUSSELS,BELGIUM
关键词
MARIJUANA; CANNABIS; CANNABINOID RECEPTOR; D(1)-RECEPTOR; RECEPTOR AUTORADIOGRAPHY; BASAL GANGLIA; HUMAN BRAIN;
D O I
10.1016/0304-3940(92)90845-X
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The distribution of cannabinoid receptor binding sites has been studied in the basal ganglia of 3 human adults using the synthetic cannabinoid agonist [H-3]CP55,940 and autoradiography. The [H-3]CP55,940-specific labeling was found in the caudate, putamen, accumbens, substantia nigra pars reticulata, and globus pallidus. The binding was consistently higher in the medial over the lateral part of the globus pallidus.
引用
收藏
页码:7 / 9
页数:3
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