ADVANCED PRIMARY NON-HODGKINS-LYMPHOMA OF THE SMALL-INTESTINE IN CHILDHOOD - REPORT OF 4 CASES

被引:5
作者
WATANABE, Y
ITO, T
HORIBE, K
ISHIGURO, Y
NIMURA, Y
机构
[1] First Department of Surgery, Nagoya University School of Medicine, Showa-ku, Nagoya, 466
[2] Department of Surgery, Branch Hospital, Nagoya University School of Medicine, Higashi-ku, Nagoya, 466
[3] Department of Pediatrics, Nagoya University School of Medicine, Showa-ku, Nagoya, 466
来源
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY | 1994年 / 24卷 / 11期
关键词
NON-HODGKINS LYMPHOMA; SMALL INTESTINE; CHILDREN;
D O I
10.1007/BF02215819
中图分类号
R61 [外科手术学];
学科分类号
摘要
Primary non-Hodgkin's lymphoma of the small intestine (PLI) is an uncommon malignancy in childhood which carries a poor prognosis. Consideration of the possible diagnosis of PLI is important when children have vague abdominal symptoms, since thoughtful multidisciplinary treatment can result in a better prognosis. This paper reports the cases of four children who have presented to our hospital since 1985 with advanced stage III or IV PLI, All the children had a huge abdominal mass but none of them had complete intestinal obstruction. Regarding the diagnosis, ultrasonography frequently reveals a hypoechoic thickening of the intestinal wall with dilated intestinal loops. A delayed primary or second-look operation may be the treatment of choice following adequate chemotherapy, while total parenteral nutritional support may prevent gastrointestinal complications. Three of the four patients have been in complete remission for 2 to 4 1/2 years since their initial treatment.
引用
收藏
页码:1023 / 1027
页数:5
相关论文
共 18 条
[1]  
Wollner N., Wachtel A.E., Exelby P.R., Centore D., Improved prognosis in children with intra-abdominal nonHodgkin's lymphoma following LSA2L2 protocol chemotherapy, Cancer, 45, pp. 3034-3039, (1980)
[2]  
Shamberger R.C., Weinstein H.J., The role of surgery in abdominal Burkitt's lymphoma, J Pediatr Surg, 27, pp. 236-240, (1992)
[3]  
LaQuaglia M.P., Stolar C.J.H., Krailo M., Exelby P., Siegel S., Meadows A., Hammond D., The role of surgery in abdominal non-Hodgkin's lymphoma: Experience from the children's cancer study group, J Pediatr Surg, 27, pp. 230-235, (1992)
[4]  
Fleming I.D., Turk P.S., Murphy S.B., Crist W.M., Santana V.M., Rao B.N., Surgical implications of primary gastrointestinal lymphoma of childhood, Arch Surg, 125, pp. 252-256, (1990)
[5]  
Hande K.R., Fisher R.I., DeVita V.T., Chabner B.A., Young R.C., Diffuse histiocytic lymphoma involving the gastrointestinal tract, Cancer, 41, pp. 1984-1989, (1978)
[6]  
Murphy S.B., Hustu H.O., A randomized trial of combined modality therapy of childhood non-Hodgkin's lymphoma, Cancer, 45, pp. 630-637, (1980)
[7]  
National Cancer Institute sponsored study of classifications of non-Hodgkin's lymphoma: Summary and description of a working formulation for clinical usage, Cancer, 49, pp. 2112-2135, (1982)
[8]  
Kobayashi M., Ueda K., Experience of treatment B-ALL/NHL in children (in Japanese), Shonigan (Pediatr Oncol), 28, pp. 312-316, (1991)
[9]  
Japanese surgical malignant tumor registration in childhood in 1990 (in Japanese), Nippon Shounigeka Gakkai Zasshi (J Jpn Pediatr Surg), 28, pp. 119-140, (1992)
[10]  
Morgan D.R., Holgate C.S., Dixon M.F., Bird C.C., Primary small intestinal lymphoma: A study of 39 cases, J Pathol, 147, pp. 211-221, (1985)