SYNAPTOLYTIC EFFECT OF THIAMINE RELATED TO ITS INTERACTION WITH NEUROTRANSMITTERS

被引：26

作者：

GALZIGNA, L

机构：

[1] Groupe de Recherches sur la Pathologie Cellulaire et Moléculaire du Globule Rouge (INSERM), B.P. 1018

[2] On leave of absence from the Institute of Biological Chemistry, University of Padova

来源：

BIOCHEMICAL PHARMACOLOGY | 1969年 / 18卷 / 10期

关键词：

D O I：

10.1016/0006-2952(69)90364-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Thiamine interacts in vitro with acetylcholine, norepinephrine and serotonin yielding molecular complexes. Such interaction can be related to the physiological effect of thiamine which, in large doses, induces a general synaptolysis. © 1969.

引用

页码：2485 / &

共 18 条

[1] ISOMERIC 2-ACETOXYTROPINE METHIODIDES [J].

ARCHER, S ;

LANDS, AM ;

LEWIS, TR .

JOURNAL OF MEDICINAL & PHARMACEUTICAL CHEMISTRY, 1962, 5 (03) :423-&

[2]

BEAVEN G. H., 1961, ADVAN SPECTROSCOPY, V2, P331

[3] A SPECTROPHOTOMETRIC INVESTIGATION OF THE INTERACTION OF IODINE WITH AROMATIC HYDROCARBONS [J].

BENESI, HA ;

HILDEBRAND, JH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1949, 71 (08) :2703-2707

[4] THE ROLE OF HYDROGEN BONDING IN THE N-]PI-STAR BLUE-SHIFT PHENOMENON [J].

BREALEY, GJ ;

KASHA, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (17) :4462-4468

[5] THE MECHANISM OF THIAMINE ACTION .2. RAPID DEUTERIUM EXCHANGE IN THIAZOLIUM SALTS [J].

BRESLOW, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (07) :1762-1763

[6]

DE CASTRO J, 1962, Agressologie, V3(Special), P127

[7]

DE CASTRO J., 1965, ACTA ANAESTH [PADOVA], V16, P33

[8] OPTICAL PROPERTIES OF MOLECULAR AGGREGATES .I. CLASSICAL MODEL OF ELECTRONIC ABSORPTION + REFRACTION [J].

DEVOE, H .

JOURNAL OF CHEMICAL PHYSICS, 1964, 41 (02) :393-&

[9]

ECKART T, 1962, ARZ FORSCH, V12, P8

[10]

GRITTI G, 1968, PERSONAL COMMUNICATI

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