Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains

被引:317
作者
Laemmli, Ulrich K. [1 ]
Kaes, Emmanuel [1 ]
Poljak, Leonora [1 ]
Adachi, Yasuhisa [1 ]
机构
[1] Univ Geneva, Dept Biochem & Mol Biol, 30 Quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
关键词
D O I
10.1016/S0959-437X(05)80285-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
It has been proposed that scaffold-associated regions are DNA elements that form the bases of chromatin loops in eukaryotic cells. Recent evidence supports a role for these elements as cis-acting 'handlers' of both structural and functional chromatin domains.u
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页码:275 / 285
页数:11
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