PHORBOL ESTER DRAMATICALLY INCREASES INCIDENCE OF METHOTREXATE-RESISTANT MOUSE CELLS - POSSIBLE MECHANISMS AND RELEVANCE TO TUMOR PROMOTION

被引：179

作者：

VARSHAVSKY, A

机构：

来源：

CELL | 1981年 / 25卷 / 02期

关键词：

D O I：

10.1016/0092-8674(81)90074-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：561 / 572

页数：12

共 38 条

[1]

ALT FW, 1978, J BIOL CHEM, V253, P1357

[2]

Andersson P, 1980, Adv Cancer Res, V33, P109, DOI 10.1016/S0065-230X(08)60670-3

[3] INDUCTION OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN [J].

BERTINO, JR ;

GABRIO, BW ;

DONOHUE, DM ;

SILBER, R ;

SIMMONS, B ;

HUENNEKENS, FM .

JOURNAL OF CLINICAL INVESTIGATION, 1963, 42 (04) :466-&

[4] METAPHASE CHROMOSOME ANOMALY - ASSOCIATION WITH DRUG-RESISTANCE AND CELL-SPECIFIC PRODUCTS [J].

BIEDLER, JL ;

SPENGLER, BA .

SCIENCE, 1976, 191 (4223) :185-187

[5] DEVELOPMENT OF RESISTANCE TO METHOTREXATE IN A MOUSE MELANOMA CELL-LINE .1. CHARACTERIZATION OF THE DIHYDROFOLATE REDUCTASES AND CHROMOSOMES IN SENSITIVE AND RESISTANT CELLS [J].

BOSTOCK, CJ ;

CLARK, EM ;

HARDING, NGL ;

MOUNTS, PM ;

TYLERSMITH, C ;

VANHEYNINGEN, V ;

WALKER, PMB .

CHROMOSOMA, 1979, 74 (02) :153-177

[6]

BOTCHAN M, 1978, COLD SPRING HARB SYM, V43, P709

[7]

Boutwell R K, 1974, CRC Crit Rev Toxicol, V2, P419

[8]

CADMAN E, 1981, J BIOL CHEM, V256, P1695

[9] THE ORIGIN OF HUMAN CANCERS [J].

CAIRNS, J .

NATURE, 1981, 289 (5796) :353-357

[10]

Diamond L, 1980, Adv Cancer Res, V32, P1, DOI 10.1016/S0065-230X(08)60360-7

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