GENE STRUCTURE OF RAT CHOLECYSTOKININ TYPE-A RECEPTOR

被引：37

作者：

TAKATA, Y

TAKIGUCHI, S

FUNAKOSHI, A

KONO, A

机构：

[1] KYUSHU NATL CANC CTR,DIV CHEMOTHERAPY,FUKUOKA 815,JAPAN

[2] KYUSHU NATL CANC CTR,DIV GASTROENTEROL,FUKUOKA 815,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 213卷 / 03期

关键词：

D O I：

10.1006/bbrc.1995.2222

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Little is known about the gene structure and mRNA expression of cholecystokinin type-A(CCKA) receptor in animals or in human. By screening an EMBL phage library containing partially digested Long-Evans rat DNA, we isolated 7 genomic clones covering a continuous 27 kb region over which a rat CCKA receptor gene spanned. The gene is approximately 10 kb in length containing the entire coding region of the rat CCKA receptor cDNA and consists of five exons interrupted by four introns. The expected sizes of the transcripts from the initiation sites were consistent with the results of northern blot analyses. (C) 1995 Academic Press, Inc.

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页码：958 / 966

页数：9

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