SYNTHESIS OF A POTENT BETA-LACTAMASE INHIBITOR-1,1-DIOXO-6-(2-PYRIDYL)METHYLENEPENICILLANIC ACID AND ITS REACTION WITH SODIUM METHOXIDE

被引：46

作者：

CHEN, YL

CHANG, CW

HEDBERG, K

机构：

来源：

TETRAHEDRON LETTERS | 1986年 / 27卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(00)84819-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

收藏

页码：3449 / 3452

页数：4

相关论文

共 24 条

[1]

ADAM S, Patent No. 50805

[2] MECHANISM OF INACTIVATION OF TEM-1 BETA-LACTAMASE BY 6-ACETYLMETHYLENEPENICILLANIC ACID [J].

ARISAWA, M ;

ADAM, S .

BIOCHEMICAL JOURNAL, 1983, 211 (02) :447-454

[3] 6-ACETYLMETHYLENEPENICILLANIC ACID (RO 15-1903), A POTENT BETA-LACTAMASE INHIBITOR .1. INHIBITION OF CHROMOSOMALLY AND R-FACTOR-MEDIATED BETA-LACTAMASES [J].

ARISAWA, M ;

THEN, RL .

JOURNAL OF ANTIBIOTICS, 1982, 35 (11) :1578-1583

[4] 6-(METHOXYMETHYLENE)PENICILLANIC ACID - INACTIVATOR OF RTEM BETA-LACTAMASE FROM ESCHERICHIA-COLI [J].

BRENNER, DG ;

KNOWLES, JR .

BIOCHEMISTRY, 1984, 23 (24) :5839-5846

[5] PENICILLANIC ACID SULFONE - AN UNEXPECTED ISOTOPE EFFECT IN THE INTERACTION OF 6-ALPHA-MONODEUTERIO AND 6-BETA-MONODEUTERIO AND OF 6,6-DIDEUTERIO DERIVATIVES WITH RTEM BETA-LACTAMASE FROM ESCHERICHIA-COLI [J].

BRENNER, DG ;

KNOWLES, JR .

BIOCHEMISTRY, 1981, 20 (13) :3680-3686

[6] PENICILLANIC ACID SULFONE - NATURE OF IRREVERSIBLE INACTIVATION OF RTEM BETA-LACTAMASE FROM ESCHERICHIA-COLI [J].

BRENNER, DG ;

KNOWLES, JR .

BIOCHEMISTRY, 1984, 23 (24) :5833-5839

[7] INACTIVATION OF RTEM BETA-LACTAMASE FROM ESCHERICHIA-COLI BY CLAVULANIC ACID AND 9-DEOXYCLAVULANIC ACID [J].

CHARNAS, RL ;

KNOWLES, JR .

BIOCHEMISTRY, 1981, 20 (11) :3214-3219

[8] CHEMICAL STUDIES ON INACTIVATION OF ESCHERICHIA-COLI RTEM BETA-LACTAMASE BY CLAVULANIC ACID [J].

CHARNAS, RL ;

FISHER, J ;

KNOWLES, JR .

BIOCHEMISTRY, 1978, 17 (11) :2185-2189

[9] INACTIVATION OF BACILLUS-CEREUS BETA-LACTAMASE-I BY 6-BETA-BROMOPENICILLANIC ACID - MECHANISM [J].

COHEN, SA ;

PRATT, RF .

BIOCHEMISTRY, 1980, 19 (17) :3996-4003

[10] INHIBITION OF THE RTEM BETA-LACTAMASE FROM ESCHERICHIA-COLI - INTERACTION OF THE ENZYME WITH DERIVATIVES OF OLIVANIC ACID [J].

EASTON, CJ ;

KNOWLES, JR .

BIOCHEMISTRY, 1982, 21 (12) :2857-2862