INTERMEDIARY METABOLISM IN THE SWARM RAT CHONDROSARCOMA CHONDROCYTE

被引：25

作者：

SPENCER, CA ^{[1
]}

PALMER, TN ^{[1
]}

MASON, RM ^{[1
]}

机构：

[1] UNIV LONDON,CHARING CROSS & WESTMINSTER MED SCH,DEPT BIOCHEM,FULHAM PALACE RD,LONDON W6 8RF,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1990年 / 265卷 / 03期

关键词：

D O I：

10.1042/bj2650911

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The rat chondrosarcoma chondrocyte has the dual capacity to metabolize glucose (mainly via glycolysis) and glutamine (via an oxidative pathway). Glutamine metabolism, unlike that of glucose, is unable to sustain intracellular ATP concentrations. Glutamine consumption by the chondrosarcoma chondrocyte, however, is significantly in excess of its utilization as an amide-group donor in hexosamine synthesis, implying a novel and major role in cell metabolism.

引用

页码：911 / 914

页数：4

共 26 条

[1] FUEL UTILIZATION IN COLONOCYTES OF THE RAT [J].