OPEN LUNG-BIOPSY OF PATIENTS WITH RHEUMATOID-ARTHRITIS

被引：49

作者：

HAKALA, M

PAAKKO, P

HUHTI, E

TARKKA, M

SUTINEN, S

机构：

[1] Department of Internal Medicine, University of Oulu, Oulu

[2] Department of Pathology, University of Oulu, Oulu

[3] Department of Surgery, University of Oulu, Oulu

[4] Mjölbolsta Hospital, Meltola

来源：

CLINICAL RHEUMATOLOGY | 1990年 / 9卷 / 04期

关键词：

RHEUMATOID NODULES; BRONCHIOLITIS; PNEUMOCONIOSIS; RHEUMATOID FACTOR;

D O I：

10.1007/BF02030506

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In order to shed light on the histological changes occurring in the lungs of patients with rheumatoid arthritis (RA), we scrutinized an open lung biospy file of 199 patients and selected the patients with RA. The histopathological patterns observed were: pulmonary rheumatoid nodules (4 cases, including one with rheumatoid pneumoconiosis); usual interstitial pneumonia (UIP) (2 cases); desquamative interstitial pneumonia (2 cases); bronchiolitis obliterans with patchy organizing pneumonia (2 cases); follicular brochiolitis (1 case); organizing pneumonia always associated with bronchiolitis (3 cases); granulomatous reaction (3 cases); obliterating vasculitis (3 cases); granulomatous vasculitis (1 case); lymphoid hyperplasia (2 cases); and localized pulmonary fibrosis (1 case). The clinical data and laboratory findings for the histopathological groups overlapped and did not properly predict the anatomical picture. Both patients with UIP died of lung disease. Otherwise the prognosis in the series was good.

引用

页码：452 / 460

页数：9

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