REACTIONS OF 1.0 NANOMETRE DIAMETER PU-238 DIOXIDE PARTICLES WITH RAT LUNG FLUID

被引：16

作者：

COOPER, JR

STRADLING, GN

SMITH, H

BREADMORE, SE

机构：

[1] National Radiological Protection Board, Harwell, Didcot, Oxon

来源：

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 1979年 / 36卷 / 05期

关键词：

D O I：

10.1080/09553007914551251

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The reactions of 1·0 nm particles of plutonium-238 dioxide with rat lung fluid have been studied both in vivo and in vitro. In both cases two products have been identified, (i) plutonium-labelled pulmonary surfactant and (ii) a heterogeneous plutonium-labelled material isolated by column chromatography. The formation of plutonium-labelled pulmonary surfactant results in the rapid translocation of plutonium from lungs to blood and in a high urinary excretion relative to administered plutonium citrate. © 1979 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：453 / 466

页数：14

共 16 条

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