BIOCHEMICAL AND RADIOLOGIC-DIAGNOSIS OF CUSHINGS-SYNDROME

Technologic advances during the past decade have greatly improved the biochemical and radiologic diagnosis of Cushing's syndrome. This article describes how the introduction of a specific and sensitive immunoradiometric assay for ACTH, CRH stimulation testing, inferior petrosal sinus sampling for ACTH, computed tomography, and MR imaging of the pituitary and adrenal glands have provided the necessary tools for an accurate diagnosis and differential diagnosis of Cushing's syndrome.