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INDIVIDUAL METABOLIC ANATOMY OF REPEATING WORDS DEMONSTRATED BY MRI-GUIDED POSITRON EMISSION TOMOGRAPHY

被引：40
作者：
HERHOLZ, K
PIETRZYK, U
KARBE, H
WURKER, M
WIENHARD, K
HEISS, WD
机构：
[1] MAX PLANCK INST NEUROL RES,COLOGNE,GERMANY
[2] UNIV COLOGNE,NEUROL KLIN,W-5000 COLOGNE,GERMANY
来源：
NEUROSCIENCE LETTERS | 1994年 / 182卷 / 01期
关键词：
SPEECH; PET; METABOLIC ACTIVATION;
D O I：
10.1016/0304-3940(94)90202-X
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The anatomical localization of brain areas involved in repeating words was examined in six right-handed non-aphasic subjects. Their individual metabolic activation was studied with positron emission tomography (PET) and [F-18]2-fluoro-2-deoxy-D-glucose (FDG) using a new data processing technique that includes three-dimensional coregistration with magnetic resonance images. Left superior temporal gyrus (cortical convexity surface, Brodmann area 22), right superior temporal lobe (superior temporal sulcus and bottom of transverse sulcus), sensorimotor cortex (vocalization area) bilaterally, and supplementary motor cortex were consistently activated in each individual. Cerebellar activation was more variable. In contrast to previous blood flow activation studies with averaging across subjects, this new technique permits the anatomical localization and quantitation of activated areas in each individual. It can therefore also be applied to patients with brain lesions.
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页码：47 / 50
页数：4
相关论文
共 18 条
[1]   REPRODUCIBILITY OF CEREBRAL GLUCOSE METABOLIC MEASUREMENTS IN RESTING HUMAN-SUBJECTS [J].
BARTLETT, EJ ;
BRODIE, JD ;
WOLF, AP ;
CHRISTMAN, DR ;
LASKA, E ;
MEISSNER, M .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1988, 8 (04) :502-512
[2]   THE ANATOMY OF PHONOLOGICAL AND SEMANTIC PROCESSING IN NORMAL SUBJECTS [J].
DEMONET, JF ;
CHOLLET, F ;
RAMSAY, S ;
CARDEBAT, D ;
NESPOULOUS, JL ;
WISE, R ;
RASCOL, A ;
FRACKOWIAK, R .
BRAIN, 1992, 115 :1753-1768
[3]  
FRACKOWIAK RSJ, 1994, TRENDS NEUROSCI, V1, P109
[4]   THE CORTICAL LOCALIZATION OF THE LEXICONS - POSITRON EMISSION TOMOGRAPHY EVIDENCE [J].
HOWARD, D ;
PATTERSON, K ;
WISE, R ;
BROWN, WD ;
FRISTON, K ;
WEILLER, C ;
FRACKOWIAK, R .
BRAIN, 1992, 115 :1769-1782
[5]   REPRODUCIBILITY OF CEREBRAL GLUCOSE-UTILIZATION MEASURED BY PET AND THE [F-18] 2-FLUORO-2-DEOXY-D-GLUCOSE METHOD IN RESTING, HEALTHY-HUMAN SUBJECTS [J].
MAQUET, P ;
DIVE, D ;
SALMON, E ;
VONFRENCKEL, R ;
FRANCK, G .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1990, 16 (4-6) :267-273
[6]   THE CORTICAL REPRESENTATION OF SPEECH [J].
MAZOYER, BM ;
TZOURIO, N ;
FRAK, V ;
SYROTA, A ;
MURAYAMA, N ;
LEVRIER, O ;
SALAMON, G ;
DEHAENE, S ;
COHEN, L ;
MEHLER, J .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1993, 5 (04) :467-479
[7]   ECHO-PLANAR MAGNETIC-RESONANCE-IMAGING STUDIES OF FRONTAL-CORTEX ACTIVATION DURING WORD GENERATION IN HUMANS [J].
MCCARTHY, G ;
BLAMIRE, AM ;
ROTHMAN, DL ;
GRUETTER, R ;
SHULMAN, RG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (11) :4952-4956
[8]   INDIVIDUAL VARIABILITY IN CORTICAL LOCALIZATION OF LANGUAGE [J].
OJEMANN, GA .
JOURNAL OF NEUROSURGERY, 1979, 50 (02) :164-169
[9]   POSITRON EMISSION TOMOGRAPHIC STUDIES OF THE CORTICAL ANATOMY OF SINGLE-WORD PROCESSING [J].
PETERSEN, SE ;
FOX, PT ;
POSNER, MI ;
MINTUN, M ;
RAICHLE, ME .
NATURE, 1988, 331 (6157) :585-589
[10]   THE PROCESSING OF SINGLE WORDS STUDIED WITH POSITRON EMISSION TOMOGRAPHY [J].
PETERSEN, SE ;
FIEZ, JA .
ANNUAL REVIEW OF NEUROSCIENCE, 1993, 16 :509-530
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