REGIOSELECTIVE 2-ACYLATION OF N-SUBSTITUTED PYRROLES BY INTRAMOLECULAR DELIVERY

被引：5

作者：

JEFFORD, CW

TANG, Q

BOUKOUVALAS, J

机构：

[1] Department of Organic Chemistry, University of Geneva

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)94412-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-substituted pyrroles prepared from α-amino acids are converted to their mixed anhydrides by treatment with an acid chloride and base. Subsequent treatment with AlCl3 brings about rearrangement to the corresponding 2-acyl derivatives in overall yields of 55-81%. © 1990.

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页码：995 / 998

页数：4

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