TL-201 SCINTIGRAPHY IN THE STAGING OF LUNG-CANCER, BREAST-CANCER AND LYMPHOMA

被引:50
作者
SEHWEIL, AM [1 ]
MCKILLOP, JH [1 ]
MILROY, R [1 ]
SAYED, MA [1 ]
ZIADA, G [1 ]
BANHAM, SW [1 ]
DAVIDSON, KG [1 ]
RAGIB, A [1 ]
OMAR, YT [1 ]
ABDELDAYEM, HM [1 ]
机构
[1] KUWAIT UNIV,DEPT NUCL MED,KUWAIT,KUWAIT
关键词
D O I
10.1097/00006231-199004000-00002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
To evaluate201T1 in the detection of the primary tumour, lymph node involvement and mediastinal spread we have studied a total of 188 patients with histologically proven lung cancer, breast cancer or malignant lymphoma. Ten patients with benign lung disease were also examined. Static images were performed 20 min after intravenous injection of 75 MBq of thallous (201T1) chloride. The results were compared with those of standard staging procedures including CT scanning and mediastinal exploration. Thallium-201 imaging was highly sensitive in detecting the primary tumour (lung cancer 86%, breast carcinoma 100%, lymphoma 85%), but showed low sensitivity in detecting mediastinal spread or lymph node involvement. Thallium-201 uptake was also observed in active sarcoidosis (one case) and active TB (two cases). We conclude that201T1 imaging is unlikely to have a clinically useful role in the diagnosis or staging of lung cancer, breast cancer or lymphoma. © 1990 Chapman and Hall Ltd.
引用
收藏
页码:263 / 269
页数:7
相关论文
共 9 条
[1]  
Cox P.H., Belfer A.J., Van Der Pompe W.B., Thallium-201 chloride uptake in tumours, a possible complication in heart scintigraphy, Brit J Rndiol, 49, pp. 767-768, (1976)
[2]  
Tonami N., Michigishi T., Bunko H., Kuwajima K., Hisada K., Clinical tumour scanning with Tl-201 chloride, J Nucl Med, 18, (1977)
[3]  
Ochi H., Sawa H., Fukuda T., Kuwajima A., Inoue Y., Nakajima H., Masuda Y., Okamura T., Onayama Y., Sugano S., Ohkita H., Tei Y., Kamino K., Kobayashi Y., Thallium-201 chloride thyroid scintigraphy to evaluate benign and/or malignant nodules - usefulness of the delayed scan, Cancer, 50, pp. 236-240, (1982)
[4]  
Hoefnagel C.A., Delprat C.C., Marcuse H.R., Viljder J., Role of Thallium-201 total body scintigraphy in follow up of thyroid carcinoma, J Nucl Med, 27, pp. 1854-1857, (1986)
[5]  
Kaplan W.D., Takvorian T., Morris J.H., Rumbaugh C.L., Connolly B.T., Atkins H.L., Thallium-201 brain tumour imaging: A comparative study with pathologic correlation, J Nucl Med, 28, pp. 47-52, (1987)
[6]  
Sehweil A., McKillop J.H., Wilson R., Milroy R., Abdel-Dayem H.M., Oam Y.T., Mechanism of Thallium-201 uptake in tumours, Eur J Nucl Med, (1990)
[7]  
Sehweil A., McKillop J.H., Ziada G., Al-Sayed M., Abdel-Dayem H.M., Omar Y.T., The optimum time for tumour imaging with Thallium-201, Eur J Nucl Med, 13, pp. 526-529, (1988)
[8]  
Rigler G., Earliest roentgenographic signs of carcinoma of the lung, JAMA, 195, (1966)
[9]  
Linde R., Basso L., Hodgkin's disease with hypercalcaemia detected by thallium-201 scintigraphy, J Nucl Med, 28, pp. 112-115, (1987)