RETINAL DOPAMINE AND LENS-INDUCED REFRACTIVE ERRORS IN CHICKS

被引：89

作者：

GUO, SS

SIVAK, JG

CALLENDER, MG

DIEHLJONES, B

机构：

[1] UNIV WATERLOO,SCH OPTOMETRY,WATERLOO,ON N2L 3G1,CANADA

[2] UNIV WATERLOO,DEPT BIOL,WATERLOO,ON N2L 3G1,CANADA

来源：

CURRENT EYE RESEARCH | 1995年 / 14卷 / 05期

基金：

加拿大自然科学与工程研究理事会;

关键词：

DOPAMINE; REFRACTIVE ERRORS; LENS-INDUCED; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC); CHICKS;

D O I：

10.3109/02713689508999936

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

This study investigated the relationship between retinal dopamine and lens induced refractive errors in chicks by high performance liquid chromatography with ultraviolet detection (HPLC-UV). After two weeks of lens wear, the chick eyes treated with +10D lenses were hyperopic (+8.29 +/- 0.43D), while the eyes treated with -10D lenses were myopic (-11.69 +/- 0.74D). At the same time, in myopic eyes the level of retinal dopamine and its metabolite 3,4-dihydroxy-phenylacetic acid (DOPAC) were reduced compared to control eyes, while in hyperopic eyes the level of retinal dopamine and DOPAC were increased as compared with control eyes. Therefore, retinal dopamine may participate in the development of lens induced refractive errors in chicks.

引用

页码：385 / 389

页数：5

共 26 条

[1] A SIMPLE MECHANISM FOR EMMETROPIZATION WITHOUT CUES FROM ACCOMMODATION OR COLOR [J].