RAPID, STABILITY-INDICATING, HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC DETERMINATION OF THEOPHYLLINE, GUAIFENESIN, AND BENZOIC-ACID IN LIQUID AND SOLID PHARMACEUTICAL DOSAGE FORMS

被引：24

作者：

HEIDEMANN, DR

机构：

[1] Analytical Research Department, Dorsey Laboratories (Division of Sandoz, Inc.), Lincoln, Nebraska

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1979年 / 68卷 / 04期

关键词：

Benzoic acid—analysis; high‐pressure liquid chromatography; in liquid and solid pharmaceutical dosage forms; stability; Guaifenesin—analysis; High‐pressure liquid chromatography—analysis of theophylline; guaifenesin; benzoic acid in liquid and solid pharmaceutical dosage forms; Theophylline—analysis;

D O I：

10.1002/jps.2600680443

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Theophylline, guaifenesin, and benzoic acid were determined by reversed‐phase high‐pressure liquid chromatography without interference from active and/or vehicle decomposition. A degradation product of sucrose, 5‐hydroxymethylfurfural, can be identified and quantified in liquid samples simultaneously. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：530 / 532

页数：3

共 25 条

[1] IMPROVED THEOPHYLLINE SERUM ANALYSIS BY AN APPROPRIATE INTERNAL STANDARD FOR GAS-CHROMATOGRAPHY
BAILEY, DG
DAVIS, HL
JOHNSON, GE
[J]. JOURNAL OF CHROMATOGRAPHY, 1976, 121 (02): : 263 - 268
[2] CHAE YS, 1976, J PHARM SCI, V65, P1179
[3] Cohen JL., 1975, ANAL PROFILES DRUG S, V4, P466
[4] DETERMINATION OF THEOPHYLLINE AND ITS METABOLITES BY LIQUID-CHROMATOGRAPHY
DESIRAJU, RK
SUGITA, ET
MAYOCK, RL
[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1977, 15 (12) : 563 - 568
[5] COMPARISON OF REACTIVITY OF AMPHETAMINE METHAMPHETAMINE AND DIMETHYLAMPHETAMINE WITH LACTOSE AND RELATED COMPOUNDS
DUVALL, RN
KOSHY, KT
PYLES, JW
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (04) : 607 - &
[6] DETERMINATION OF THEOPHYLLINE IN PLASMA ULTRAFILTRATE BY REVERSED PHASE HIGH-PRESSURE LIQUID-CHROMATOGRAPHY
FRANCONI, LC
HAWK, GL
SANDMANN, BJ
HANEY, WG
[J]. ANALYTICAL CHEMISTRY, 1976, 48 (02) : 372 - 375
[7] HABERLI E, 1959, Pharm Acta Helv, V34, P65
[8] A KINETIC STUDY OF GLUCOSE DEGRADATION IN ACID SOLUTION
HEIMLICH, KR
MARTIN, AN
[J]. JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 1960, 49 (09): : 592 - 597
[9] GAS CHROMATOGRAPHIC DETERMINATION OF GLYCEROL GUAIACOLATE IN PHARMACEUTICAL PREPARATIONS
HUDANICK, J
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (02) : 238 - &
[10] JENSEN F, 1977, MEDD NOR FARM SELSK, V39, P38

← 1 2 3 →