COPPER(I)-INDUCED ADDITION OF AMINES TO UNACTIVATED NITRILES - THE 1ST GENERAL ONE-STEP SYNTHESIS OF ALKYL AMIDINES

被引：125

作者：

ROUSSELET, G ^{[1
]}

CAPDEVIELLE, P ^{[1
]}

MAUMY, M ^{[1
]}

机构：

[1] ESPCI,CNRS,RECH ORGAN LAB,10 RUE VAUQUELIN,F-75231 PARIS 05,FRANCE

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 40期

关键词：

AMIDINES; NITRILES; AMINES; COPPER(I)-CATALYZED CONDENSATION;

D O I：

10.1016/0040-4039(93)85054-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cu(I)Cl promotes the condensation of acetonitrile la and benzonitrile lb with primary and secondary amines 2a-g into amidines 3a-j under mild conditions, in high to quantitative yields. Stoichiometric formation Of Cu(I)-amidines complexes allows to control the degree of substitution of resulting amidines

引用

页码：6395 / 6398

页数：4

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