TISSUE SPECIFIC REGULATION OF PROSTAGLANDIN PRODUCTION - STIMULATION OF 6-KETOPROSTAGLANDIN-F1-ALPHA BIOSYNTHESIS BY RAT-KIDNEY CYTOSOL

被引：4

作者：

MORITA, I

MUROTA, SI

机构：

[1] Department of Pharmacology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 582卷 / 01期

关键词：

(Bovine seminal vesicles; Kidney; Liver; Carrageenin granuloma); 6-Ketoprostaglandin F[!sub]1α[!/sub; Prostaglandin synthesis;

D O I：

10.1016/0304-4165(79)90300-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Boiled cytosol of various rat tissues each affected prostaglandin biosynthesis by bovine seminal vesicle microsomes in a specific way. Kidney cytosol enhanced 6-ketoprostaglandin F1.alpha. production in a dose-dependent manner. This stimulatory effect was lost after dialysis. Liver, spleen and carrageenan granuloma cytosol inhibited 6-ketoprostaglandin F1.alpha. production but enhanced prostaglandin E2 production.

引用

页码：173 / 178

页数：6

共 26 条

[1] PROSTAGLANDINS - MEMBERS OF A NEW HORMONAL SYSTEM [J].