5-AMINOTHIAZOLES FROM DITHIOCARBOXYLIC ESTERS AND ALPHA-AMINOACETONITRILE

被引：9

作者：

THIEL, W

机构：

来源：

JOURNAL FUR PRAKTISCHE CHEMIE | 1990年 / 332卷 / 06期

关键词：

D O I：

10.1002/prac.19903320604

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Carbamoyldithiocarboxylicesters 1 and heteroaryldithiocarboxylic esters 2 react with alpha-aminoacetonitriles under mild conditions to form 2-carbamoyl-5-aminothiazoles 5 or 2-heteroaryl-5-aminothiazoles 6. The intermediate N-cyanomethylthiooxamides 3 can be isolated. The 2-heteroaryl-5-aminothiazoles 6 and their acyl derivatives 7 are highly fluorescent, in contrast to the azomethines 8 derived from 6.

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页码：845 / 852

页数：8

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