2 CASES OF FATAL INTOXICATION DUE TO TRANYLCYPROMINE OVERDOSE

被引：8

作者：

BONIFACE, PJ

机构：

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1991年 / 15卷 / 01期

关键词：

D O I：

10.1093/jat/15.1.38

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Two cases of death following the ingestion of tranylcypromine are presented. High concentrations of tranylcypromine were determined in blood, urine, and liver by gas-liquid chromatography. Tranylcypromine was extracted from buffered blood with n-butyl chloride. The evaporated extract was derivatized with trifluoroacetic anhydride and analyzed by gas chromatography with nitrogen-phosphorus selective detection. The method was linear in blood over the range 0.5-20 mg/L with a limit of quantitation of about 0.2 mg/L.

引用

页码：38 / 40

页数：3

共 11 条

[1]

ANDERSON WH, 1989, ADV ANAL TOXICOLOGY, V2, pCH2

[2]

BABIAK W, 1961, CAN MED ASSOC J, V85, P377

[3] SUCCESSFUL SUICIDE WITH TRANYLCYPROMINE SULFATE [J].

BACON, GA .

AMERICAN JOURNAL OF PSYCHIATRY, 1962, 119 (06) :585-&

[4]

BASSETT RC, 1979, J ANAL TOXICOL, V1, P168

[5] OVERDOSE OF PARSTELIN (TRANYLCYPROMINE) [J].

GRIFFITHS, GJ .

MEDICINE SCIENCE AND THE LAW, 1973, 13 (02) :93-94

[6]

HARRINGTON, 1975, METHODOLOGY ANAL TOX, V1, P27

[7] FATAL INTOXICATION DUE TO TRANYLCYPROMINE [J].

MACKELL, MA ;

CASE, ME ;

POKLIS, A .

MEDICINE SCIENCE AND THE LAW, 1979, 19 (01) :66-68

[8]

Mawdsley J A, 1968, Med J Aust, V2, P292

[9]

MOFFAT AC, 1986, CLARKS ISOLATION IDE, P1035

[10]

REYNOLDS JEF, 1989, MARTINDALE EXTRA PHA, P381

← 1 2 →