ACTIVATION OF NEUTROPHILS BY A CHEMICALLY SEPARATED BUT OPTICALLY COUPLED NEUTROPHIL POPULATION UNDERGOING RESPIRATORY BURST

被引：48

作者：

SHEN, X ^{[1
]}

MEI, W ^{[1
]}

XU, X ^{[1
]}

机构：

[1] TECHNOL CTR,INST BIOPHYS,KAISERSLAUTERN,GERMANY

来源：

EXPERIENTIA | 1994年 / 50卷 / 10期

关键词：

NEUTROPHIL; INTERCELLULAR COMMUNICATION; OPTICAL COUPLING; RESPIRATORY BURST; LOW-LEVEL CHEMILUMINESCENCE;

D O I：

10.1007/BF01923488

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Neutrophils from pig blood were used as a model system to investigate the optical communication between cells. It was found that neutrophils stimulated to undergo respiratory burst can activate a second, chemically separated, but optically coupled population of neutrophils. The response of the latter was visualized as a temporary rising of their low-level chemiluminescence and an enhanced generation of superoxide radicals detected by both the reduction of ferricytochrome c and spin trapping. The results provide evidence that a long-range optical coupling of biological significance between living cells exists.

引用

页码：963 / 968

页数：6

共 20 条

[1] CHEMI-LUMINESCENCE FROM EUKARYOTIC AND PROKARYOTIC CELLS - REDUCING POTENTIAL AND OXYGEN REQUIREMENTS [J].