EFFECT OF SURAMIN (BAYER 205) ON RENAL ORNITHINE DECARBOXYLASE ACTIVITY AND POLYAMINE CONCENTRATIONS IN RATS

被引：7

作者：

SELMECI, L

POSCH, E

SIMON, G

HARSING, L

机构：

[1] Institute of Pathopysiology Semmelweis University Medical School Nagyvarad ter 4., H-1445 Budapest

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)91682-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

After a single high dose (20 mg/100 g i.v.) of suramin ornithine decarboxylase activity was increased rapidly in the rat kidney. Enzyme kinetic measurements indicate that on the basis of Km values renal ornithine decarboxylases from control or suramin treated rats are indistinguishable. Renal nucleic acid and polyamine levels were also enhanced in response to suramin. Changes observed in this study are considered as biochemical signs of induced renal growth. © 1979.

引用

页码：323 / 329

页数：7

共 22 条

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