SPECIFICITY AND REACTIVITY OF CYTOPLASMIC AND NUCLEOLAR ANTIBODY IN SLE SERA

被引：15

作者：

WATANABE, N

FISHER, HM

EPSTEIN, WV

机构：

[1] American Rheumatism Associations, San Francisco, California

[2] National Institutes of Health, San Francisco, California

[3] University of California Medical Center, San Francisco, California

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 03期

关键词：

D O I：

10.1002/art.1780120303

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The serum of 2 of 31 patients with SLE was found to contain an antibody to a previously unrecognized RNA‐containing antigen found in human mononuclear cell cytoplasm and nucleolus. When tissue fixed, this antibody proved capable of fixing the patient's own rheumatoid factor and human complement components. No recognizable inhibition of complement fixation by rheumatoid factor could be demonstrated by the fluorescent antibody technic. Copyright © 1969 American College of Rheumatology

引用

页码：173 / &

共 25 条

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[2] CLARK G, 1967, ARTHRITIS RHEUM, V10, P272
[3] A DIALYSIS TECHNIQUE FOR PREPARING FLUORESCENT ANTIBODY
CLARK, HF
SHEPARD, CC
[J]. VIROLOGY, 1963, 20 (04) : 642 - &
[4] CLINE MJ, 1965, PHYSL REV, V45, P675
[5] DAUSSET J, 1965, NY ACAD SCI, V124, P550
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[7] DAVIS JS, 1966, ARTHRITIS RHEUM, V9, P499
[8] DEICHER HRG, 1960, ARTHRITIS RHEUM, V31, P1
[9] Doniach D, 1966, Clin Exp Immunol, V1, P237
[10] ELLING P, 1967, ACTA PATHOL MIC SC, V69, P384

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