BINDING AND DETOXIFICATION OF HEAVY-METALS IN LOWER-VERTEBRATES WITH REFERENCE TO METALLOTHIONEIN

被引：196

作者：

HOGSTRAND, C

HAUX, C

机构：

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY | 1991年 / 100卷 / 1-2期

关键词：

D O I：

10.1016/0742-8413(91)90140-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The metabolism of Cu, Zn, Cd and Hg in lower vertebrates is described, using fish as a model. 2. The main part of this review deals with metallothionein and the role of this protein for the storage and detoxification of these metals. 3. Factors influencing the bioavailability and probable uptake routes are identified. 4. The distribution of the metals within the organism is outlined. The distribution between tissues is described and the subcellular distribution discussed with reference to metallothionein.

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页码：137 / 141

页数：5

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