10-YEAR TO 20-YEAR CLINICAL-RESULTS AFTER SHORT ESOPHAGOMYOTOMY WITHOUT AN ANTIREFLUX PROCEDURE (MODIFIED HELLER OPERATION) FOR ESOPHAGEAL ACHALASIA

被引:47
作者
ELLIS, FH
WATKINS, E
GIBB, SP
HEATLEY, GJ
MOGHISSI, K
RIBET, M
机构
[1] Departments of Thoracic and Cardiovascular Surgery and Gastroenterology, Sias Surgical Research Unit, Lahey Clinic Medical Center, Burlington, MA
[2] Division of Cardiothoracic Surgery, New England Deaconess Hospital, Boston, MA
关键词
ESOPHAGOMYOTOMY; ACHALASIA; ESOPHAGUS; DYSPHAGIA; ESOPHAGITIS;
D O I
10.1016/1010-7940(92)90080-H
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To determine the long-term clinical results after modified esophagomyotomy without an antireflux procedure for esophageal achalasia, the status of all patients undergoing this operation with a minimum follow-up time of 10 years was reviewed; 81 such patients were operated on between January 1970 and January 1981. Thirteen patients were lost to follow-up review permitting clinical evaluation during the past year of 68 patients (84%) observed for a median of 13.6 years. Fifty-nine patients (87%) were improved by operation; 90% of the patients who underwent a primary procedure were improved, whereas only 73% of patients undergoing reoperation benefited. Kaplan-Meier analysis of the results of all 81 patients disclosed an improvement rate of 98.5% at 5 years, 95.6% at 10 years, 85.8% at 15 years, and 67.3% at 20 years. When the level of improvement or lack thereof was analyzed, the percentage of excellent results decreased from 54% to 32% (P = 0.02). The percentage of good results remained the same, whereas fair or poor results together increased from 20% to 37% (P = 0.05). Neither age, sex, esophageal caliber, duration of symptoms, or previous therapy appeared to influence these results. We conclude that limited esophagomyotomy without an antireflux procedure results in persistent long-term improvement for the patient with esophageal achalasia. The level of improvement, however, decreases with the passage of time, presumably because of persistent disease in the body of the esophagus leading to impaired esophageal emptying in some patients and late reflux esophagitis in other patients owing to poor esophageal clearance.
引用
收藏
页码:86 / 90
页数:5
相关论文
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