INVITRO ANTIVIRAL ACTIVITY OF PROPOLIS

被引：90

作者：

AMOROS, M ^{[1
]}

SAUVAGER, F ^{[1
]}

GIRRE, L ^{[1
]}

CORMIER, M ^{[1
]}

机构：

[1] FAC PHARM RENNES,MICROBIOL PHARMACEUT LAB,RENNES,FRANCE

来源：

APIDOLOGIE | 1992年 / 23卷 / 03期

关键词：

PROPOLIS; HERPES SIMPLEX VIRUS; ADENOVIRUS; VESICULAR STOMATITIS VIRUS; POLIOVIRUS; ANTIVIRAL ACTIVITY;

D O I：

10.1051/apido:19920306

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

The in vitro effect of propolis on several DNA and RNA viruses including herpes simplex type 1, an acyclovir resistant mutant, herpes simplex type 2, adenovirus type 2, vesicular stomatitis virus and poliovirus type 2, was investigated. The inhibition of poliovirus propagation was clearly observed through a plaque reduction test and a multistep virus replication assay with a selectivity index equal to 5. At the concentration of 30-mu-g/ml, propolis reduced the titer of herpes simplex viruses by 1 000, whereas vesicular stomatitis virus and adenovirus were less susceptible. In addition to its effect on virus multiplication, propolis was also found to exert a virucidal action on the enveloped viruses HSV and VSV.

引用

页码：231 / 240

页数：10

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