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SOLVENT NEPHROTOXICITY IN HUMANS AND EXPERIMENTAL-ANIMALS

被引：20
作者：
NELSON, NA
ROBINS, TG
PORT, FK
机构：
[1] UNIV MICHIGAN, DEPT EPIDEMIOL, ANN ARBOR, MI 48109 USA
[2] UNIV MICHIGAN, DEPT INTERNAL MED, ANN ARBOR, MI 48109 USA
来源：
AMERICAN JOURNAL OF NEPHROLOGY | 1990年 / 10卷 / 01期
关键词：
Hydrocarbons; Kidney diseases; Occupational diseases; Solvents;
D O I：
10.1159/000168048
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Evidence from human case reports, epidemiologic studies and animal experiments have suggested that exposure to organic solvents is associated with a wide spectrum of renal disorders, including tubular necrosis, interstitial disease, glomerulonephritis and neoplasia. This review summarizes what is known about solvent-induced renal damage in humans and experimental animals, with emphasis on hypothesized mechanisms by which this broad range of disorders may occur. © 1990 S. Karger AG, Basel.
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页码：10 / 20
页数：11
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