CHOLECYSTOKININ-TETRAPEPTIDE INDUCES PANIC ATTACKS IN PATIENTS WITH PANIC DISORDER

被引：227

作者：

BRADWEJN, J

KOSZYCKI, D

METERISSIAN, G

机构：

[1] CARLETON UNIV,PSYCHOL,OTTAWA K1S 5B6,ONTARIO,CANADA

[2] MCGILL UNIV,PSYCHIAT,MONTREAL H3A 2T5,QUEBEC,CANADA

来源：

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE | 1990年 / 35卷 / 01期

关键词：

D O I：

10.1177/070674379003500115

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Cholecystokinin-tetrapeptide (CCK-4) and placebo were injected to 11 panic disorder patients. CCK-4 induced a panic attack identical to spontaneous panic attacks in all patients; placebo did not induce any attacks. The role of CCK-4 in anxiety disorders is discussed.

引用

页码：83 / 85

页数：3

共 10 条

[1] CHOLECYSTOKININ IN THE CENTRAL NERVOUS-SYSTEM - A MINIREVIEW
BEINFELD, MC
[J]. NEUROPEPTIDES, 1983, 3 (06) : 411 - 427
[2] BENZODIAZEPINES ANTAGONIZE CHOLECYSTOKININ-INDUCED ACTIVATION OF RAT HIPPOCAMPAL-NEURONS
BRADWEJN, J
DEMONTIGNY, C
[J]. NATURE, 1984, 312 (5992) : 363 - 364
[3] EFFECTS OF PK-8165, A PARTIAL BENZODIAZEPINE RECEPTOR AGONIST, ON CHOLECYSTOKININ-INDUCED ACTIVATION OF HIPPOCAMPAL PYRAMIDAL NEURONS - A MICROIONTOPHORETIC STUDY IN THE RAT
BRADWEJN, J
DEMONTIGNY, C
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1985, 112 (03) : 415 - 418
[4] CHIODO A, 1983, SCIENCE, V196, P998
[5] DEMONTIGNY C, 1988, 11TH ANN SCI M CAN C
[6] GOLTERMANN NR, 1980, J BIOL CHEM, V255, P6181
[7] THE EFFECTS OF CHOLECYSTOKININ-LIKE PEPTIDES IN SCHIZOPHRENICS AND NORMAL HUMAN-SUBJECTS
HOMMER, DW
PICKAR, D
CRAWLEY, JN
WEINGARTNER, H
PAUL, SM
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1985, 448 (JUL) : 542 - 552
[8] CHOLECYSTOKININ-LIKE PEPTIDES POTENTIATE APOMORPHINE-INDUCED INHIBITION OF DOPAMINE NEURONS
HOMMER, DW
SKIRBOLL, LR
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1983, 91 (01) : 151 - 152
[9] NEURONAL CHOLECYSTOKININ - ONE OR MULTIPLE TRANSMITTERS
REHFELD, JF
[J]. JOURNAL OF NEUROCHEMISTRY, 1985, 44 (01) : 1 - 10
[10] CHOLECYSTOKININ RECEPTORS IN THE BRAIN - CHARACTERIZATION AND DISTRIBUTION
SAITO, A
SANKARAN, H
GOLDFINE, ID
WILLIAMS, JA
[J]. SCIENCE, 1980, 208 (4448) : 1155 - 1156

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