DELETION ANALYSIS OF MALE-STERILITY EFFECTS OF TERT-HAPLOTYPES IN THE MOUSE

被引:8
作者
BENNETT, D
ARTZT, K
机构
[1] Department of Zoology, The University of Texas at Austin, Austin
关键词
D O I
10.1017/S0016672300035278
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
We present data on the effects of three chromosome 17 deletions on transmission ratio distortion (TRD) and sterility of several t-haplotypes. All three deletions have similar effects on male TRD: that is, Tdel/tcomplete genotypes all transmit their t–haplotype in very high proportion. However, each deletion has different effects on sterility of heterozygous males, with Tor/t being fertile, Thp/t less fertile, and Torl/t still less fertile. These data suggest that wild-type genes on chromosomes homologous to f-haplotypes can be important regulators of both TRD and fertility in males, and that the wild-type genes concerned with TRD and fertility are at least to some extent different. The data also provide a rough map of the positions of these genes. © 1990, Cambridge University Press. All rights reserved.
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页码:179 / 183
页数:5
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