SCREENING OF ORGANIC-ACIDS IN URINE BY CHEMICAL IONIZATION MASS-SPECTROMETRY

被引：14

作者：

ISSACHAR, D

YINON, J

机构：

[1] Department of Isotope Research, Weizmann Institute of Science, Rehovot

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 02期

关键词：

D O I：

10.1002/bms.1200060203

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A method has been developed for qualitative screening of carboxylic acids in human urine. The method uses direct chemical ionization mass spectrometry with isobutane as reagent gas. The carboxylic acids are separated from the urine samples by ion exchange. Normal carboxylic acid profiles have been determined and are compared with the profiles of patients suffering from certian metabolic disorders. Copyright © 1979 Heyden & Son Ltd

引用

页码：47 / 56

页数：10

共 33 条

[1] ANBAR M, 1976, CLIN CHEM, V22, P1503
[2] BJORKMAN L, 1976, CLIN CHEM, V22, P49
[3] QUANTITATIVE EXTRACTION AND GAS-LIQUID CHROMATOGRAPHIC DETERMINATION OF ORGANIC ACIDS IN URINE
CHALMERS, RA
[J]. ANALYST, 1972, 97 (1161) : 958 - 967
[4] CONSALAZIO DF, 1963, PHYSL MEASUREMENTS M, P448
[5] CHEMICAL IONIZATION MASS SPECTROMETRY OF COMPLEX MOLECULES - ESTERS OF DICARBOXYLIC AND TRICARBOXYLIC ACIDS
FALES, HM
MILNE, GWA
NICHOLSO.RS
[J]. ANALYTICAL CHEMISTRY, 1971, 43 (13) : 1785 - &
[6] MASS-SPECTRA OF CARBOXYLIC-ACIDS .6. METASTABLE DISSOCIATIONS OF ISOMERIC IONS IN MASS-SPECTRA OF OXALIC AND FORMIC ACIDS, AND MALONIC AND ACETIC-ACIDS
HOLMES, JL
[J]. ORGANIC MASS SPECTROMETRY, 1973, 7 (03): : 341 - 346
[7] HORNING EC, 1970, METHOD MED RES, V12, P368
[8] DIAGNOSIS OF DISORDERS IN AMINO-ACID METABOLISM BY CHEMICAL IONIZATION MASS-SPECTROMETRY
ISSACHAR, D
YINON, J
[J]. CLINICA CHIMICA ACTA, 1976, 73 (02) : 307 - 314
[9] ISSACHAR D, UNPUBLISHED
[10] ISSACHAR D, 1977, 25TH ANN C MASS SPEC, P242

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