GEM-DIFLUOROALLYLLITHIUM - PREPARATION BY THE TRANSMETALATION PROCEDURE AND SOME REACTIONS

被引：28

作者：

SEYFERTH, D

WURSTHORN, KR

机构：

[1] Department of Chemistry, Massachusetts Institute of Technology, Cambridge

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1979年 / 182卷 / 04期

关键词：

D O I：

10.1016/S0022-328X(00)83935-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

3,3-Difluoroallyltrimethyltin has been prepared by the reaction of β-trimethylstannylethylidenetriphenylphosphorane with chlorodifluoromethane. This tin compound reacts with n-butyllithium in tetrahydrofuran at -95°C to generate gem-difluoroallyllithium. The latter, however, is not stable in solution at that temperature. If generated in situ in the presence of a triorganochlorosilane, products of the type R3SiCF2CHCH2 are obtained in good yield. Addition to the CO bond of 3-pentanone to give (C2H5)2C(OH)CF2CHCH2 was achieved by the method of alternate, incremental additions. © 1979.

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页码：455 / 464

页数：10

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