COMPREHENSIVE EVALUATION OF ACUTE IMMUNOLOGICAL CHANGES INDUCED BY CUPROPHANE AND POLYSULFONE MEMBRANES IN A PATIENT ON CHRONIC-HEMODIALYSIS

被引：8

作者：

PATARCA, R ^{[1
]}

PEREZ, G ^{[1
]}

GONZALEZ, A ^{[1
]}

GARCIAMORALES, RO ^{[1
]}

GAMBLE, R ^{[1
]}

KLIMAS, N ^{[1
]}

FLETCHER, MA ^{[1
]}

机构：

[1] VET ADM MED CTR,MIAMI,FL

来源：

AMERICAN JOURNAL OF NEPHROLOGY | 1992年 / 12卷 / 04期

关键词：

CUPROPHANE; POLYSULFONE; CYTOKINES; MESSENGER RNA; PHYTOHEMAGGLUTININ; LYMPHOID CELL PHENOTYPES; POLYMERASE CHAIN REACTION;

D O I：

10.1159/000168459

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We have investigated the acute changes in cytokine gene expression patterns and immune status in vivo and ex vivo in a patient on chronic hemodialysis with cuprophane membranes before and after two hemodialysis sessions with either cuprophane or polysulfone membranes. Results show that both dialyzer membranes have differential acute effects on the immune system and that the concomitant use of reverse-transcriptase-coupled polymerase chain reaction, solid-phase and radioimmunoassays, and flow-cytometric analysis may be useful in the longitudinal assessment of patients on chronic hemodialysis.

引用

页码：274 / 278

页数：5

共 14 条

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