PRODUCTION AND REGULATION OF GELATINASE-B BY HUMAN T-CELLS

被引：67

作者：

MONTGOMERY, AMP

SABZEVARI, H

REISFELD, RA

机构：

[1] Department of Immunology, The Scripps Research Institute, La Jolla, CA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1176卷 / 03期

关键词：

GELATINASE-B; METALLOPROTEINASE; T-LYMPHOCYTE; INTERLEUKIN-2;

D O I：

10.1016/0167-4889(93)90054-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Here we describe for the first time the production of gelatinase B (MMP 9; 92-kDa type IV collagenase) by human peripheral blood T-lymphocytes. Expression of this enzyme was found to be dependent on the activation status of these T-cells and to be regulated by Interleukin-2.

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页码：265 / 268

页数：4

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