PHOTOCHEMISTRY OF A MACROMOLECULE - TOBACCO MOSAIC VIRUS

被引：8

作者：

MCLAREN, AD

机构：

[1] College of Agricultural Sciences, University of California, Berkeley, California

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1968年 / 8卷 / 06期

关键词：

D O I：

10.1111/j.1751-1097.1968.tb05896.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abstract— A history of the photochemistry of the first known virus is presented. Hollaender and Duggar recognized that the virus contains nucleic acid because of the shape of their action spectrum for photoinactivation. An analysis of this spectrum in detail presents a challenge to photochemists because of the combined role of protein and nucleic acid in determining rates of inactivation. At present these rates can not be explained simply on the basis of the photochemistry of each of the constituents; that is, the photochemistry of free infectious nucleic acid differs in several respects from that exhibited by nucleic acid irradiated in intact virus. At present it is believed that pyrimidine hydrate and dimer formations are important, but an explicit solution to the problem is not in sight. Copyright © 1968, Wiley Blackwell. All rights reserved

引用

页码：521 / &

共 45 条

[1] PHOTOREACTIVATION OF NUCLEIC ACID FROM TOBACCO MOSAIC VIRUS [J].