SUPEROXIDE ANION PRODUCTION BY CIRCULATING POLYMORPHONUCLEAR LEUKOCYTES IN RHEUMATOID-ARTHRITIS

被引：12

作者：

CENCETTI, A ^{[1
]}

DEMARTINO, M ^{[1
]}

GRAZIANI, E ^{[1
]}

BONGI, SM ^{[1
]}

PALERMO, C ^{[1
]}

PAVARI, E ^{[1
]}

ZOPPI, M ^{[1
]}

机构：

[1] UNIV FLORENCE,MED 1 CLIN,VIALE GB MORGAGNI 85,I-50134 FLORENCE,ITALY

来源：

CLINICAL RHEUMATOLOGY | 1990年 / 9卷 / 01期

关键词：

Polymorphonuclear Leucocytes; Rheumatoid Arthritis; Superoxide Anion;

D O I：

10.1007/BF02030242

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In twelve rheumatoid arthritis (RA)patients, receiving only nonsteroid antiinflammatory therapy, Superoxide anion (0 2 - ) generation by polymorphonuclear leucocytes (PMNs) was assessed by Cytochrome C reduction. The 0 2 - production by nonactivated PMNs in RA patients was significantly higher than in healthy controls. The 0 2 - production by PMNs activated by zymosan and phorbol myristate acetate was significantly lower than in controls. PMNs from controls preincubated with rheumatoid sera generated higher 0 2 - levels than the same PMNs incubated in normal sera. © 1990 Springer-Verlag.

引用

页码：51 / 55

页数：5

共 23 条

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