NATURE OF THE NITRIC-OXIDE COMPLEXES OF LIPOXYGENASE

被引：54

作者：

SALERNO, JC ^{[1
]}

SIEDOW, JN ^{[1
]}

机构：

[1] DUKE UNIV,DEPT BOT,DURHAM,NC 27706

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 579卷 / 01期

基金：

美国国家卫生研究院;

关键词：

(ESR); Lipoxygenase; Nitric oxide; Spin; 3/2; iron;

D O I：

10.1016/0005-2795(79)90104-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The NO complex of lipoxygenase with EPR signals near g = 4.0 is an S = 3/2 system with D ≈ 15 cm-1 similar to Fe2+-EDTA-NO. This may result from antiferromagnetic coupling of axial (D ≫ E) high spin ferrous iron to NO. The other NO complex of lipoxygenase, with EPR signals below ge, may result from rhombic high spin ferrous iron coupled to NO with D > J. The quenching of both signals by a hydroperoxy derivative of linoleic acid probably represents replacement of NO by an oxygen ligand. © 1979.

引用

页码：246 / 251

页数：6

共 15 条

[1]

BONNER WD, 1978, FRONTIERS BIOL ENERG

[2]

BUTLER WF, 1978, BIOPHYS J, V21, pA8

[3] SOYBEAN LIPOXYGENASE - IRON-CONTAINING DIOXYGENASE [J].