A WATER-SOLUBLE PRODRUG OF TAXOL WITH SELF-ASSEMBLING PROPERTIES

被引：52

作者：

NICOLAOU, KC ^{[1
]}

GUY, RK ^{[1
]}

PITSINOS, EN ^{[1
]}

WRASIDLO, W ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO, DEPT CHEM, LA JOLLA, CA 92093 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 15-16期

关键词：

D O I：

10.1002/anie.199415831

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Just as effective and not as toxic, taxol derivative 1 displays antitumor activity comparable to that of the parent compound. Since 1 is water soluble, complications that arise in clinical applications of taxol may be avoided. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1583 / 1587

页数：5

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