The findings reported in the literature on the relationship between social support and adaptation to illness are ambiguous and, in some cases, contradictory. The present study sought to examine the relationship among support factors, medical status, and adaptation to chronic illness in 36 hemodialysis patients. Social support was measured on three dimensions: family environment (family cohesion and family expressiveness), level of spouse support, and presence of a confidant. Adaptation was assessed in terms of morale and changes in social functioning since the onset of dialysis. Data collection was done through unstructured interviews, mailed questionnaires, observation, and review of medical records. Correlation coefficients showed a positive association between the measures of social support and morale and a negative correlation among family cohesion, presence of a confidant, and changes in social functioning. Copyright © 1979 Wiley Periodicals, Inc., A Wiley Company