COLLECTINS - PATTERN-RECOGNITION MOLECULES INVOLVED IN 1ST LINE HOST DEFENSE

被引：200

作者：

SASTRY, K ^{[1
]}

EZEKOWITZ, RA ^{[1
]}

机构：

[1] HARVARD UNIV,CHILDRENS HOSP,DEPT PEDIAT,DEPT HEMATOL ONCOL & INFECT DIS,BOSTON,MA 02115

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 01期

关键词：

D O I：

10.1016/0952-7915(93)90082-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A group of chimeric molecules comprising globular heads, which contain the carbohydrate recognition domain, and collagen tails are defined as collectins. The mannose-binding proteins, pulmonary surfactant apoproteins A and D and conglutinin all qualify as members of this family, whose function appears to be as pattern recognition molecules involved in the first line of defense in the pre-immune host.

引用

页码：59 / 66

页数：8

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