IN-VITRO INHIBITION OF CYCLOOXYGENASE AND 5-LIPOXYGENASE BY ALKAMIDES FROM ECHINACEA AND ACHILLEA SPECIES

被引：101

作者：

MULLERJAKIC, B

BREU, W

PROBSTLE, A

REDL, K

GREGER, H

BAUER, R

机构：

[1] UNIV MUNICH, INST PHARMAZEUT BIOL, D-80333 MUNICH, GERMANY

[2] UNIV WIEN, INST BOT, VERGLEICHENDE PHYTOCHEM ABT, A-1030 VIENNA, AUSTRIA

[3] UNIV DUSSELDORF, INST PHARMAZEUT BIOL, D-40225 DUSSELDORF, GERMANY

来源：

PLANTA MEDICA | 1994年 / 60卷 / 01期

关键词：

ACHILLEA SPECIES; ECHINACEA ANGUSTIFOLIA; ANACYCLUS PYRETHRUM; AARONSOHNIA PUBESCENS; COMPOSITAE; UNSATURATED ALKAMIDES; CYCLOOXYGENASE INHIBITION; 5-LIPOXYGENASE INHIBITION;

D O I：

10.1055/s-2006-959404

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Polyunsaturated alkamides isolated from Achillea species, Echinacea angustifolia DC., Anacyclus pyrethrum (L.) Link, and Aaronsohnia pubescens (Desf.) Bremer & Humphries, (Compositae) were shown to possess inhibitory activity in in vitro cyclooxygenase (sheep seminal microsomes) and 5-lipoxygenase (porcine leukocytes) assays. Activity appeared to depend on the particular structure of the alkamides.

引用

页码：37 / 40

页数：4

共 19 条

[1] ALKAMIDES FROM THE ROOTS OF ECHINACEA-ANGUSTIFOLIA [J].