DERIVATIZATION OF POSTTRANSLATIONALLY MODIFIED AMINO-ACIDS

被引:24
作者
TEERLINK, T
机构
[1] Department of Clinical Chemistry, Free University Hospital, 1007 MB Amsterdam
来源
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 1994年 / 659卷 / 1-2期
关键词
D O I
10.1016/0378-4347(94)00147-2
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
After a brief overview of posttranslational modifications of protein amino acids, the use of various derivatizing reagents for amino acid analysis is discussed. Derivatization and chromatographic separation of hydroxyproline, methylhistidine, and phosphorylated amino acids are discussed in detail to illustrate some of the strategies that can be applied to the analysis of posttranslationally modified amino acids.
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页码:185 / 207
页数:23
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