BREAST MR-IMAGING WITH COMMERCIALLY AVAILABLE TECHNIQUES - RADIOLOGIC-PATHOLOGICAL CORRELATION

被引:95
作者
FOBBEN, ES [1 ]
RUBIN, CZ [1 ]
KALISHER, L [1 ]
DEMBNER, AG [1 ]
SELTZER, MH [1 ]
SANTORO, EJ [1 ]
机构
[1] ST BARNABAS HOSP,DEPT SURG,LIVINGSTON,NJ 07039
关键词
BREAST NEOPLASMS; MR; GADOLINIUM; MAGNETIC RESONANCE (MR); CONTRAST ENHANCEMENT; RECEIVER OPERATING CHARACTERISTIC (ROC);
D O I
10.1148/radiology.196.1.7784558
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To evaluate the clinical utility of dynamic gadolinium-enhanced magnetic resonance (MR) imaging of the breast with commercially available techniques in patients scheduled for excisional biopsy. MATERIALS AND METHODS: A total of 91 breast abnormalities, 70 benign and 21 malignant, were evaluated. Thin-section three-dimensional gradient-echo images were obtained before and 2, 4, and 7 minutes after injection of contrast material. Three radiologists prospectively evaluated the mammograms and MR images. RESULTS: The areas under the receiver operating characteristic curves were 0.820: for mammography and 0.893 for MR imaging (P = .67). Sensitivity of MR imaging was 82.5%, compared with 74.6% for mammography. Specificity of MR imaging was 82.5%, compared with 79.1% for mammography. Enhancement profiles showed early intense enhancement hi malignancies but considerable overlap with enhancement of benign disease. CONCLUSION: Breast MR imaging is a slightly more sensitive modality than mammography but not a highly specific technique for evaluating breast lesions. It has utility in several clinical situations but should not be used as a substitute for biopsy or general screening.
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页码:143 / 152
页数:10
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