IMPROVED ERYTHROCYTE SURVIVAL WITH HIGH-DOSE VITAMIN-E IN CHRONIC HEMOLYZING G6PD AND GLUTATHIONE SYNTHETASE DEFICIENCIES

被引：62

作者：

SPIELBERG, SP ^{[1
]}

BOXER, LA ^{[1
]}

CORASH, LM ^{[1
]}

SCHULMAN, JD ^{[1
]}

机构：

[1] INDIANA UNIV, SCH MED, INDIANAPOLIS, IN 46204 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1979年 / 90卷 / 01期

关键词：

D O I：

10.7326/0003-4819-90-1-53

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The origin of the malignant 'hairy cells' of leukemic reticuloendotheliosis remains controversial. A continuous cell line, designated 4972, was recently established from the spleen of a 30-yr-old black man with leukemic reticuloendotheliosis. We have found this cell line to be infected with Epstein-Barr virus (EBV). Because surface receptors for EBV and infection with the virus are restricted to B lymphocytes among cells found in the blood, the presence of EBV in these 'hairy cells' further supports the B-lymphocyte origin of the malignant cells in at least some patients with leukemic reticuloendotheliosis.

引用

页码：53 / 54

页数：2

共 12 条

[1]

ALLEN DW, 1978, J LAB CLIN MED, V91, P321

[2] EFFECT OF ANTIOXIDANTS ON CULTURED HUMAN DIPLOID FIBROBLASTS EXPOSED TO CYSTINE-FREE MEDIUM [J].