COMPLEMENT ACTIVATION EARLY IN ENDOTOXIN-SHOCK

被引:30
作者
HEIDEMAN, M
KAIJSER, B
GELIN, LE
机构
[1] UNIV GOTHENBURG,DEPT SURG 1,S-40033 GOTHENBURG 33,SWEDEN
[2] UNIV GOTHENBURG,INST MED MICROBIOL,S-40033 GOTHENBURG 33,SWEDEN
关键词
D O I
10.1016/0022-4804(79)90080-5
中图分类号
R61 [外科手术学];
学科分类号
摘要
The effect of endotoxin infusion was studied in dogs. Aggregation of platelets in the blood and trapping in the lung were observed. Endotoxin infusion was initially followed by leucopenia. Hemolysis of red cells corresponding to about 1% of the erythrocytes was observed. A blood pressure decrease and a tracheal insufflation pressure increase followed injury. Impaired oxygenation of arterial blood was registered. The infusion was accompanied by complement activation. Its relation to the phenomena studied is discussed. © 1979.
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页码:74 / 78
页数:5
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