VESICOURETERAL REFLUX IN THE DAMAGED NON-SCARRED KIDNEY

被引：7

作者：

STUTLEY, JE ^{[1
]}

GORDON, I ^{[1
]}

机构：

[1] HOSP SICK CHILDREN,DEPT RADIOL,GREAT ORMOND ST,LONDON WC1N 3JH,ENGLAND

来源：

PEDIATRIC NEPHROLOGY | 1992年 / 6卷 / 01期

关键词：

VESICOURETERAL REFLUX; IMPAIRED RENAL FUNCTION; GROWTH ARREST; TECHNETIUM 99M DIMERCAPTOSUCCINIC ACID;

D O I：

10.1007/BF00856824

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Renal damage without scarring is a rare manifestation of reflux nephropathy, and is infrequently reported in the literature. A retrospective review of a large series of patients with urinary tract disorders at the hospital for Sick Children, Great Ormond Street, identified 12 patients with vesico-ureteric reflux (VUR) with no evidence of scarring but with renal damage as assessed using technetium 99m dimercaptosuccinic acid (Tc-99m-DMSA) scan. There were 9 simplex kidneys, the differential function was between 33% and 43% (mean 38%). On follow-up to date (mean 6.7 years) all kidneys show stable differential function with neither improvement nor deterioration. Only 8 children had a urinary tract infection. Renal damage without evidence of a focal scar associated with VUR may be a manifestation of growth arrest possibly due to glomerular damage. The sensitivity of Tc-99m-DMSA may reveal the permanent nature of the renal damage.

引用

页码：25 / 29

页数：5

共 20 条

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